It is a critical time to formulate an organized and comprehensive approach to monitoring safety of maternal immunizations in low- and middle-income countries and thereby track safety and effectiveness to ensure program success and public confidence.

Pregnant women and their babies are among the populations most vulnerable to untoward health outcomes. Yet current standards for evaluating health interventions cannot be met during pregnancy because of lack of adequate evidence.

Although major reductions in maternal and child mortality were achieved in the Millennium Development Goals era, progress must be accelerated to meet Sustainable Development Goals health targets by 2030.